![Insulinoma Associated Antigen [IA-2 Antigen]](https://curewelldiagnostics.co.in/wp-content/uploads/2025/06/image-4.webp)
It is a blood test that helps identify antibodies associated with type 1 diabetes at an early stage. Insulinoma-associated antigen-2 (IA-2) is a protein found in insulin-producing beta cells of the pancreas.
IA-2 (Insulinoma-Associated-2 Antigen) is a protein found in pancreatic islet cells, specifically in beta cells, which produce insulin. It is one of several autoantigens targeted by the immune system in type 1 diabetes mellitus (T1DM).
The IA-2 antibody test detects autoantibodies against IA-2 in the blood. It is used to diagnose or predict type 1 diabetes and to distinguish it from type 2 or other forms of diabetes.
No Special Preparation. Informed Consent Required.
7 Day(s)*
Diabetes Endocrinology
1
The IA-2 test is helpful for:
Diagnosing type 1 diabetes
Screening at-risk individuals (e.g., family history)
Predicting disease onset in pre-symptomatic patients
Differentiating autoimmune diabetes from other types (e.g., type 2, MODY)
Children or adults with new-onset diabetes suspected to be autoimmune
People with a family history of type 1 diabetes
Patients with latent autoimmune diabetes in adults (LADA)
Clinical trials in type 1 diabetes prevention research
A blood sample is collected from a vein.
No fasting is required.
The sample is analyzed for the presence of IA-2 autoantibodies.
